Omnii-1 Omnii-1 is Radical Numerics' next-generation multimodal genome language model that unifies 28 biological modalities including DNA, RNA, proteins, and epigenomics, trained on trillions of tokens of biological data. It outperforms specialized models on tasks from regulatory genomics and protein design to cancer detection, rare disease variant prioritization, and biodefense, and designed the first AI-generated bacteriophages administered to a human patient under compassionate use.
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“Omnii-1 is out! We started training a few months ago, and the range of applications we've found that it can tackle has surprised even us. It's been a clear lesson in the power of scale — in parameters, data, context, tasks, modalities, etc. Grateful to have built it with this incredible team.”
“When we backed @RadicalNumerics, the bet was that one general model could learn the language of biology, the same way LLMs did for text. Today Omnii-1 beats AlphaGenome, designs antibodies and cancer vaccine candidates, and designed a phage covered by @carlzimmer in @NYTimes. All from one model. 🧬”
“I am actually So Impressed by how many new capabilities Omnii-1 was announced with Congrats @RadicalNumerics :)”



