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Labcorp is seeking a Medical Director, Clinical Development – MRD Portfolio (Solid Tumors) to join our team.

Work Schedule: Monday – Friday, 1st shift

Job Summary:

The Medical Director, Clinical Development – MRD Portfolio is a key physician leader responsible for shaping and executing the clinical development strategy for Labcorp Oncology's minimal residual disease (MRD) portfolio across solid tumors. This individual will provide medical leadership for the development, validation, and clinical adoption of MRD and circulating tumor DNA (ctDNA)-based technologies, advancing precision oncology through innovative molecular diagnostics that improve patient outcomes across the cancer care continuum.

As the clinical development lead for the MRD portfolio, this role will drive the generation of clinical evidence required to support product development, clinical validity, utility, reimbursement, guideline inclusion, and integration into routine oncology practice. The Medical Director will lead a team of disease-focused clinical development physicians and work closely with partners across research and development, operations, biostatistics, medical affairs, market access, regulatory affairs, commercial, and executive leadership to develop and execute a cohesive clinical strategy across multiple tumor types and indications.

The successful candidate will be a board-certified medical oncologist with broad expertise across solid tumors, a strong background in clinical research and development, and a passion for advancing the role of molecular diagnostics in cancer care. This individual will serve as a key scientific representative for Labcorp Oncology, partnering with leading investigators, professional societies, cooperative groups, payers, and other external stakeholders to establish MRD testing as a critical component of personalized cancer management.

Job Responsibilities:

Clinical Development Leadership

• Serve as the clinical development lead for Labcorp Oncology's MRD portfolio across solid tumors, providing strategic medical leadership for evidence generation, product development, and clinical adoption initiatives.
• Develop and execute the clinical development strategy supporting MRD and ctDNA-based technologies across multiple tumor types and disease settings.
• Lead the design, development, and execution of clinical studies and evidence-generation programs that establish the clinical validity, clinical utility, and health-economic value of MRD testing.
• Direct clinical strategies supporting MRD applications, including minimal residual disease detection, recurrence monitoring, treatment response assessment, risk stratification, treatment selection, and clinical trial enrichment.
• Lead the development and implementation of clinical studies that support integration of MRD testing into clinical care pathways and routine oncology practice.
• Partner with operations, biostatistics, R&D, and market access teams on study design, protocol development, endpoint selection, statistical analysis plans, study oversight, and interpretation of results.
• Recruit, engage, and maintain relationships with leading principal investigators, cooperative groups, and academic research centers to support company-sponsored clinical studies and strategic research collaborations.
• Oversee study execution in partnership with medical operations, including protocol development, site selection, enrollment strategy, timeline management, budget oversight, and study governance.
• Translate emerging clinical data into actionable clinical development recommendations and portfolio strategies.
• Support investigator-initiated studies, strategic research collaborations, and real-world evidence programs that expand the evidence base supporting MRD testing.

Portfolio and Product Leadership

• Provide medical leadership for the MRD portfolio throughout the product lifecycle, from concept development through commercialization and lifecycle management.
• Advise on product development strategy by identifying unmet clinical needs, new indication opportunities, emerging market trends, and future applications of MRD technologies.
• Define intended use populations, clinical claims, test report content, validation requirements, and evidence-generation strategies necessary to support product development and adoption.
• Partner with R&D teams to guide assay development, biomarker strategy, and next-generation product innovation.
• Evaluate competitive technologies, emerging biomarkers, and evolving standards of care to inform portfolio strategy and prioritization.
• Provide clinical input into product roadmaps, indication expansion opportunities, and future growth areas within the oncology portfolio.
• Support development of clinical and scientific evidence required for successful product launches and lifecycle management activities.

Clinical Utility, Market Access, and Adoption

• Partner with market access teams to develop and execute evidence-generation strategies supporting payer coverage, reimbursement, and health-system adoption.
• Provide medical leadership for studies designed to demonstrate clinical utility, impact on physician decision-making, patient outcomes, and economic value.
• Support interactions with payers, policy stakeholders, and guideline organizations by communicating the clinical rationale and value proposition of MRD testing.
• Contribute to strategies supporting inclusion of MRD testing within clinical practice guidelines, treatment pathways, and value-based care models.
• Ensure clinical development priorities and evidence-generation plans align with reimbursement, market access, and adoption objectives.

Investigator and External Scientific Leadership

• Build and maintain relationships with leading oncology investigators, academic medical centers, cooperative groups, and professional societies across solid tumors.
• Recruit and engage principal investigators and clinical sites to participate in company-sponsored studies and strategic collaborations.
• Serve as a scientific leader and ambassador for Labcorp Oncology within the oncology community.
• Represent Labcorp Oncology at scientific congresses, advisory boards, investigator meetings, and industry forums.
• Engage key opinion leaders to support clinical development strategy, evidence generation, and long-term portfolio planning.

Medical Affairs and Scientific Communications

• Provide medical leadership and post-launch support for MRD products, including interpretation of clinical evidence, management of complex clinical questions, and support for appropriate clinical implementation.
• Serve as a clinical resource for healthcare providers regarding MRD testing and integration of results into patient management.
• Oversee medical education initiatives and scientific communications supporting MRD adoption across solid tumors, including tumor boards, webinars, educational programs, and scientific exchange activities.
• Partner with medical affairs, commercial, and marketing teams to develop scientifically accurate and clinically meaningful educational content.
• Lead publication planning and support development of manuscripts, abstracts, presentations, congress submissions, and peer-reviewed publications.
• Maintain scientific rigor and ensure evidence is effectively communicated to diverse clinical, scientific, and payer audiences.

People Leadership

• Lead, mentor, and develop a team of medical directors and disease-specific clinical leaders supporting the MRD portfolio.
• Provide strategic oversight across disease-specific clinical development programs and evidence-generation plans.
• Establish portfolio priorities, allocate resources, and align development objectives with organizational goals and business strategy.
• Foster a culture of scientific excellence, innovation, accountability, and cross-functional collaboration.
• Develop talent and organizational capabilities that support continued growth of Labcorp Oncology's MRD and precision oncology programs.

Cross-Functional Leadership

• Collaborate closely with medical affairs, operations, biostatistics, regulatory affairs, market access, legal, compliance, commercial, and R&D teams.
• Support regulatory submissions and interactions by providing clinical expertise and scientific rationale.
• Partner with commercial leadership to ensure clinical evidence supports successful product launches and growth initiatives.
• Monitor emerging scientific, clinical, and competitive developments in oncology, molecular diagnostics, and liquid biopsy technologies to inform strategy and decision-making.

Minimum Qualifications:

• M.D. or D.O. degree from an accredited medical school.
• Board certification in Medical Oncology.
• 5 or more years of post-fellowship clinical experience treating patients with solid tumors.
• 3 or more years of oncology clinical development, clinical research, clinical trial leadership, or evidence-generation experience within the pharmaceutical, biotechnology, diagnostics, CRO, or academic research environment.
• 8 or more years of experience designing, leading, or supporting prospective and/or retrospective clinical studies, including protocol development, endpoint selection, study conduct, data analysis, interpretation, and publication of results.
• 5 or more years of experience working in cross-functional environments with operations, biostatistics, regulatory affairs, medical affairs, research & development, commercial, and/or market access teams.
• 20 or more presentations delivered to scientific congresses, investigators, key opinion leaders (KOLs), healthcare providers, advisory boards, or medical education forums.

Preferred Qualifications:

• 5 or more years of experience in molecular diagnostics, liquid biopsy, minimal residual disease (MRD), circulating tumor DNA (ctDNA), precision oncology, or biomarker-driven clinical development.
• 5 or more years of industry experience within diagnostics, biotechnology, pharmaceutical, or life sciences organizations, with responsibility for oncology product development, medical affairs, clinical development, or translational research.
• 3 or more years of experience serving as a medical lead, clinical development lead, or equivalent leadership role for an oncology assay, biomarker, diagnostic, or therapeutic development program.
• 5 or more years of experience leading oncology clinical development programs, evidence-generation initiatives, or translational research activities across multiple solid tumor indications.
• 3 or more studies or evidence-generation programs supporting clinical utility, reimbursement, payer coverage, guideline inclusion, or adoption of oncology diagnostics or precision medicine products.
• 3 or more years of experience partnering with Market Access teams to develop evidence-generation strategies supporting value demonstration, reimbursement, and commercial adoption.
• 3 or more years of direct people leadership experience, including management, mentoring, and performance development of physicians, scientists, and/or cross-functional clinical teams.
• 20 or more peer-reviewed publications, scientific presentations, and participation at major oncology congresses.
• Participation in 2 or more regulatory submissions, product launches, or major lifecycle management initiatives in oncology, molecular diagnostics, precision medicine, or related therapeutic areas.

Additional Job Standards:

• Strong understanding of oncology clinical trial methodology, study design, evidence generation, biostatistics, and regulatory requirements.
• Broad knowledge of solid tumor treatment paradigms, clinical guidelines, biomarkers, and precision oncology approaches.
• Ability to travel up to 30%, including attendance at investigator meetings, advisory boards, and scientific congresses.
• Deep understanding of oncology treatment paradigms, biomarker-driven care, clinical guidelines, and evolving precision oncology approaches across solid tumors.
• Expertise in clinical trial design, protocol development, biostatistics, epidemiology, and evidence-generation methodologies.
• Strong understanding of regulatory, compliance, and quality frameworks supporting clinical development and diagnostics.
• Demonstrated ability to evaluate complex scientific and clinical data and translate insights into development strategy.
• Strong strategic thinking and portfolio management capabilities.
• Excellent written, verbal, and presentation skills with the ability to communicate effectively across scientific, clinical, executive, commercial, and payer audiences.
• Proven ability to lead within highly matrixed organizations and influence without direct authority.
• Strong project leadership and organizational skills with the ability to manage multiple high-priority initiatives simultaneously.
• Demonstrated ability to navigate ambiguity, solve complex problems, and drive alignment across functions.
• Commitment to scientific rigor, innovation, and improving patient outcomes through precision oncology and molecular diagnostics.
• Established relationships with oncology investigators, cooperative groups, academic cancer centers, and professional societies.

Application Window: 8/12/26 - 8/31/26

Pay Range: $250k - 360K

All job offers will be based on a candidate’s skills and prior relevant experience, applicable degrees/certifications, as well as internal equity and market data. 

The position is also eligible for an annual bonus under the Labcorp Bonus Plan. Bonuses are payable based on corporate and/or business segment performance and are subject to individual performance modifiers. Compensation may also include discretionary short- and long-term incentive packages.

Benefits: Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical, Dental, Vision, Life, STD/LTD, 401(k), Paid Time Off (PTO) or Flexible Time Off (FTO), Tuition Reimbursement and Employee Stock Purchase Plan. Employees regularly scheduled to work less than 20 hours, Casual, Intern, and Temporary employees are only eligible to participate in the 401(k) Plan. For more detailed information, please click here. 

Labcorp is proud to be an Equal Opportunity Employer:

Labcorp strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. Additionally, all qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law. 

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