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Seeking Breakthrough Makers

Children’s Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation.

At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care—and your career.



CHOP does not discriminate on the basis of race, color, sex, national origin, religion, or any other legally protected categories in any employment, training, or vendor decisions or programs. CHOP recognizes the critical importance of a workforce rich in varied backgrounds and experiences and engages in ongoing efforts to achieve that through equally varied and non-discriminatory means.


A Brief Overview
Under the direction/guidance of a mentor (principal investigator), assumes responsibility for a specific, on-going research project. The experience will serve to extend, refine and enhance skills necessary for professional and career development, and will enable the individual to broaden his/her scientific background by acquiring new research capabilities. It is expected that this individual will conduct independent scholarly research, and will contribute directly to the overall research goals of the project and the research group.

This role will be expected to participate in project planning, recording and interpretation/evaluation of data, and communication of results. This position will also be expected to acquire technical, lab management, and manuscript/grant writing skills; and participate in seminars, lectures, poster sessions and presentations at national meetings. This role also may be required to supervise junior lab members, develop new methods and protocols for research, and assist with the development of other research projects in the lab.

About the Laboratory

The laboratory of Dr. Anand Bhagwat at the Children’s Hospital of Philadelphia is seeking a highly motivated and creative Postdoctoral Scholar to join an innovative new research program focused on how AML cells interact with the immune system and how this impacts outcomes for children with AML. We view immune therapies as a lens through which we can make crucial basic science discoveries about AML biology. An example of this line of investigation can be seen in Bhagwat et al., Nature Medicine 2024.

Current projects investigate:

- How the host’s inflammatory exposures alter AML phenotypes and therapy responses

- How leukemia lineage plasticity is affected by immune pressures

- How leukemia alters immune function

- Translational approaches to overcome intrinsic leukemia resistance to immune therapies

This position offers the opportunity to address original questions within the vibrant CHOP and Penn research communities

What we offer:

- A collaborative and intellectually stimulating research environment

- Access to state-of-the-art technologies and resources, including single cell genomics and epigenetic, high-parameter flow cytometry, and large biobanks of leukemia samples from both adult and pediatric patients

- Strong, available mentorship and career development support

- Frequent interactions with world-renowned investigators across the CHOP and Penn campuses

What you will do

• Conduct independent scholarly research and develop new methods and protocols
• Participate in project planning, recording and evaluation of data
• Acquire technical, lab management and grant writing skills
• Participate in seminars, lectures, poster sessions and presentation at national meetings
• Supervise junior lab members
• Assist with other research projects

Education Qualifications

• Doctorate Required

Skills and Abilities

• Ability to wear a respirator device

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must receive an annual influenza vaccine. Learn more.

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SALARY RANGE:

$20,800.00 - $110,400.00 Annually

Salary ranges are shown for full-time jobs. If you're working part-time, your pay will be adjusted accordingly.

If you are applying for a Research Post-Doctoral Fellow role, please refer to this link for salary guidelines (copy & paste into your browser): https://www.research.chop.edu/services/hiring-a-postdoctoral-fellow#collapse-accordion-3523-3

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At CHOP, we are committed to fair and transparent pay practices. Factors such as skills and experience could result in an offer above the salary range noted in this job posting. Click here for more information regarding CHOP's Compensation and Benefits.