Opal Ventures

Opal Ventures is a pre-seed health tech fund that writes $100K–$200K first checks into startups building U.S. healthcare infrastructure. Owen Willis founded it in 2023 after building On Deck Health and serving as COO of Osmosis. Its portfolio includes Superpower, Weave Bio, Orchestra Health, WellTheory, ScienceMachine and Astron Health, and Trusted Health acquired ShiftOS (formerly ShiftRx) in 2026.

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Owen Willis

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A profile about the people, projects and experiences behind their work. Discover their career, contributions and connections.

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A thoughtful collaborator who builds great products and supports the people around them.

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A thoughtful collaborator who builds great products and supports the people around them.

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Opal Ventures

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Owen Willis

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Opal Ventures

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Opal Ventures

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