PROSPR is an ARPA-H program focused on extending healthspan and addressing age-related disease. It aims to identify biochemical and physiological markers and develop assessment tools to help researchers understand and target underlying causes of age-related disease. The program also describes in-home data collection and clinical-trial protocols intended to assess age-associated health outcomes on a shorter timescale than studies that follow participants for decades. ARPA-H lists awards under PROSPR, including work on intrinsic-capacity scoring, biomarkers, and interventions.