Advanced Analysis for Precision cancer Therapy: adapting cancer treatments as tumors mutate and change.
ARPA-H’s Advanced Analysis for Precision Cancer Therapy (ADAPT) program aims to help clinicians respond to metastatic cancers as tumors change. It supports work on biomarkers and therapy recommendations using tumor biology, predictive modeling, and multimodal data. The program also includes an evolutionary clinical-trial approach that studies patients across multiple lines of treatment, and a treatment-and-analysis platform intended to support data availability and collaboration. ARPA-H describes the overall goal as predicting which patients may respond to which therapies. Its coordinated trials cover metastatic breast, colorectal, and lung cancers.
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