One Comprehensive Universal Radiotherapy for Everyone: radiotherapy technology for a low-cost curative treatment effective for all cancers.
ARPA-H’s One Comprehensive Universal Radiotherapy for Everyone (1-CURE) program aims to develop a rapid, low-cost radiotherapy approach for local, metastatic, and radiotherapy-resistant cancers. Its proposed strategy combines multifunctional smart radiotherapy biomaterials for image-guided targeting and sustained immunoadjuvant delivery with an Abscopal Treatment Planning System that integrates those biomaterials and ultra-high dose-rate FLASH radiotherapy. The program’s goal is to improve systemic anti-tumor responses across cancer types; this is a research and development objective, not an established treatment.
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