At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
 

Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.
 

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Job Description
 

Senior Director, HIV Treatment Portfolio Strategy

 

The Senior Director, HIV Treatment Portfolio Strategy is responsible for defining and advancing the integrated portfolio strategy across Gilead's HIV Treatment brands. As the portfolio expands to include multiple complementary brands, this leader ensures brand strategies, investments, and commercial approaches work together intentionally to maximize long-term patient impact, portfolio value, and franchise growth while preserving clear brand-level ownership and accountability.

 

This role serves as the enterprise integrator for the HIV Treatment business, partnering closely with Brand Leadership, Sales, Medical Affairs, Market Access, Insights & Analytics, Finance, Commercial Operations, and Global teams to identify portfolio opportunities, establish strategic priorities, guide investment and resource allocation decisions, and enable coordinated decision-making across brands. The role is accountable for portfolio direction, governance, prioritization, and strategic integration, while brand and capability leaders translate those priorities into specialized strategies, activation plans, and business outcomes.

 

The Senior Director identifies and frames the portfolio's most consequential strategic choices, evaluates opportunities, risks, dependencies, and trade-offs across brands, and develops objective recommendations that enable timely executive decisions and coordinated organizational action. This includes assessing growth opportunities, competitive responses, investment trade-offs, and future priorities.

 

Key Responsibilities

 

The Senior Director, Portfolio Strategy is accountable for defining the integrated HIV Treatment portfolio strategy, establishing portfolio priorities, leading cross-brand decision-making, and optimizing investment and resource allocation across the business.

 

The role does not own brand, customer engagement, media, digital, field, or channel strategies. Instead, it establishes the portfolio direction, priorities, governance, and decision frameworks that guide those functions. Brand teams and portfolio capability leaders translate portfolio priorities into specialized strategies, execution plans, and measurable business outcomes.

 

Portfolio Strategy, Growth & Investment Prioritization

• Lead the development and alignment of the integrated HIV Treatment Portfolio Strategy, defining the role of each brand and how brands work together to address evolving patient, customer, and market needs.
• Own the portfolio planning framework, connecting long-range strategy, annual planning, investment decisions, and business reviews into a cohesive roadmap.
• Assess market dynamics, competitive trends, customer needs, policy developments, and emerging innovations to identify the growth opportunities, risks, and strategic choices most critical to the future performance of the HIV Treatment portfolio.
• Develop recommendations on portfolio positioning, competitive responses, future growth opportunities, and strategic priorities to strengthen long-term franchise performance and competitiveness.
• Establish governance, prioritization, and decision-making processes that support effective resource allocation and resolution of cross-brand trade-offs.
• Lead portfolio investment planning and performance reviews, recommending where resources should be increased, sustained, redirected, or reduced to maximize portfolio value.
• Champion a portfolio-first mindset that balances individual brand objectives with broader franchise priorities, long-term growth, and patient impact.

 

Commercial Alignment & Operating Model

• Translate portfolio strategy into enterprise priorities, strategic guardrails, and operating principles that guide how brands work together across the HIV Treatment portfolio.

• Define governance structures, decision rights, prioritization frameworks, and planning processes that enable effective coordination across brands and functions.

• Establish portfolio priorities and strategic guardrails that brand and capability leaders use to shape customer engagement, field, digital, media, Next Best Action, and other specialized strategies.
• Ensure commercial investments are evaluated based on both brand impact and contribution to overall portfolio objectives.
• Drive alignment across cross-functional stakeholders when strategic trade-offs, competing priorities, or resource allocation decisions require enterprise-level decision making.

 

Leadership & Strategic Influence

• Align senior leaders around portfolio priorities, strategic choices, and investment decisions.
• Translate market, customer, competitive, and financial insights into clear recommendations and decision-ready options for leadership.
• Champion high-priority cross-functional initiatives requiring coordination across commercial, medical, market access, analytics, operations, and global teams.
• Bring external perspectives, emerging trends, and evolving customer needs into portfolio planning and decision-making.
• Serve as a trusted strategic advisor to senior leadership on portfolio growth, competitiveness, and long-term value creation.

 

Measures of Success

• Leadership has a clear and aligned view of portfolio priorities, strategic choices, investment needs, and the role of each brand.
• Portfolio, brand, and functional plans are connected through effective governance, coordinated decision-making, and transparent resource allocation.
• Cross-brand synergies are maximized while brand differentiation, accountability, and strategic focus are preserved.
• Portfolio resources and investments are focused on the highest-value growth opportunities and strategic priorities.
• Portfolio priorities are consistently translated into aligned strategies, coordinated execution, and sustainable franchise growth.

• Investment and resource allocation decisions consistently improve portfolio performance, strategic focus, and long-term franchise value.

Basic Qualifications

• Bachelor's degree in Business, Marketing, Life Sciences, Healthcare, Public Health, or a related field and twelve (12) years of relevant experience

OR

• Master's degree in Business, Marketing, Public Health, Life Sciences, Healthcare, or a related field and ten (10) years of relevant experience

Preferred Qualifications

• Bachelor's degree with 12+ years, or Master's degree with 10+ years of experience in pharmaceutical marketing, commercial strategy, portfolio strategy, franchise leadership, market access, sales leadership, business development, or related commercial functions.
• Significant experience within the pharmaceutical or biotechnology industry, including responsibility for strategic planning, portfolio strategy, franchise strategy, brand strategy, commercial leadership, or business performance management.
• Demonstrated success developing and implementing portfolio, franchise, or brand strategies, including identifying cross-brand opportunities, managing strategic trade-offs, and driving integrated business performance within complex and highly competitive therapeutic areas.
• Experience leading enterprise, franchise, or portfolio-level strategic planning processes, including long-range planning, annual business planning, investment prioritization, business reviews, and executive decision support.
• Experience supporting products across multiple lifecycle stages, including launch planning, growth optimization, lifecycle management and indication expansion
• Demonstrated ability to develop business cases, investment scenarios, resource-allocation recommendations, and strategic alternatives across brands, customer segments, and commercial investments.
• Deep understanding of the U.S. healthcare ecosystem, including payer dynamics, reimbursement, pricing, access, policy developments, and customer decision-making processes.
• Strong knowledge of HIV treatment markets, customers, competitive dynamics, treatment paradigms, and emerging industry trends preferred.
• Exceptional strategic, analytical, and problem-solving capabilities, with demonstrated experience framing complex business questions, evaluating risks and trade-offs, and translating ambiguity into actionable recommendations for senior leadership.
• Experience establishing portfolio planning processes, governance models, decision frameworks, resource-allocation approaches, and operating principles that enable coordinated decision-making across brands and functions.
• Demonstrated ability to balance brand-specific objectives with broader franchise and portfolio priorities, making recommendations that optimize long-term enterprise value and sustainable business growth.
• Proven ability to lead through influence and align senior stakeholders across Marketing, Sales, Medical Affairs, Market Access, Commercial Operations, Finance, Insights & Analytics, and Global organizations.
• Strong executive presence, communication, and storytelling capabilities, with experience presenting complex strategic recommendations and influencing decisions among senior leadership teams.

 

People Leader Accountabilities

Create an inclusive, high-performing environment that attracts, develops, and retains top talent while fostering collaboration, innovation, and accountability. Lead and coach Directors and Associate Directors to strengthen strategic leadership, commercial acumen, and enterprise thinking, ensuring the organization has the capabilities needed to achieve current and future business objectives. Empower teams through clear priorities, effective resource allocation, and continuous feedback while building a strong leadership pipeline and driving a culture of excellence across the HIV Treatment franchise.

 

 

The salary range for this position is: $261,375.00 - $338,250.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

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