At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary

The Molecular Technologist – Liquid Profiling is responsible for performing routine high complexity molecular techniques that include, but are not limited to, blood processing and buffy coat extraction, RNA/DNA extractions, PCR, Next-Generation Sequencing, equipment maintenance, laboratory inventory, sample tracking and receiving packages. This position works under the direction of the supervisor and follows standard laboratory procedures and policies.  Molecular Technologists develop foundational skills in molecular workflows, quality systems and data documentation while contributing to team goals.

Job Responsibilities

• Sample preparation, including blood centrifugation, plasma processing and buffy coat extractions.

• Performs RNA and DNA extractions for daily molecular testing and ensures correct patient labeling.

• Performs molecular techniques such as real-time PCR and Next-Generation Sequencing.

• Prepares Corrective and Preventive Action (CAPA) documents for nonconformance events observed during the pre-analytical, analytical, and post-analytical clinical laboratory testing.

• Participates in continuous process improvements, validations and proficiency testing.

• Tracks, enters, and monitors patient files using the Laboratory Information System.

• Maintains laboratory equipment, including completing logs and maintenance, i.e. clean, sterilize, maintain, and shut down laboratory equipment, accessories, and instruments used in research experiments, daily and weekly as required.

• Each individual performs only those high complexity tests that are authorized by the laboratory director and require a degree of skill commen­surate with the individual’s education, training or experience, and technical abilities.

• Follow the laboratory’s proce­dures for specimen handling and proc­essing, test analyses, reporting and maintain records of patient test results.

• Maintain records that dem­onstrate that proficiency testing sam­ples are tested in the same manner as patient specimens.

• Adhere to the laboratory’s quality control policies, document all quality control activities, instrument and pro­cedural calibrations and maintenance performed.

• Follow the laboratory’s estab­lished policies and procedures whenever test systems are not within the laboratory’s established acceptable lev­els of performance.

• Be capable of identifying problems that may adversely affect test performance or reporting of test results and ei­ther must correct the problems or im­mediately notify the general super­visor, technical supervisor, clinical consultant, manager or director.

• Document all corrective actions taken when test systems deviate from the laboratory’s established performance specifications.

• Perform high complexity testing under the onsite, direct supervision of a general supervisor as defined in the CLIA regulations.

• Accepts other duties as assigned.

Required Qualifications

• We are seeking to hire a Molecular Technologist with varying levels of experience.

  • Molecular Technologist I - Bachelor’s degree in scientific field required and may have less than 1 year of relevant work experience.

  • Molecular Technologist II – Bachelor’s degree in scientific field required and 3+ years of relevant molecular laboratory experience.

• Bachelor's degree in chemical, biological, clinical or medical laboratory science, or medical technology from an accredited institution.

• Demonstrate skills in technical data interpretation and ability to troubleshoot.

• Proficient in Microsoft Office programs, such as Word, Excel, and Outlook. General working knowledge of the internet for business use, and skilled in operating office equipment.

Preferred Qualifications

• Master's degree in a chemical, biological, clinical or medical laboratory science, or medical technology from an accredited institution.

• Demonstrate proficiency in technical data interpretation and ability to troubleshoot.

• RNA and DNA extraction experience.

• Nucleic acid extraction experience.

• Next Generation Sequencing experience

• Knowledge of laboratory safety procedures for biohazards and chemicals, as well as quality control procedures and regulations.

Physical Demands

• Will work at a computer some of the time as well as need to keep inventory and ordering records requiring the use of copiers and PDF scanners.

• Visual acuity and analytical skill to distinguish fine detail. Ability to pass a visual color discrimination test.

• Manual dexterity to use common laboratory equipment and perform sterile techniques as required.

• Must possess ability to sit and/or stand for long periods of time.

• Must possess ability to perform repetitive motion.

• Ability to lift up to 30 pounds.

• May be required to handle and/or may have exposure to blood-borne pathogens, extreme temperatures, high noise levels, fumes and bio-hazardous material/chemicals including formaldehyde, xylene, Clorox bleach, DAB and alcohol, which emit fumes. The formaldehyde, xylene, and DAB are carcinogenic.

Other

• This position may require evenings/nights, weekends and Holidays.

Available Shifts

• 1st Shift: 5:30am-4:00pm

• 2nd Shift: 1:30pm-12:00am

• 3rd Shift: 9:30pm-8:00am

Conditions of Employment:  Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check ( applicable for certain positions) and reference verification.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.